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艾美捷科技特约代理Epigentek公司产品。


Epigentek公司是全球领先的表观遗传学相关研究的技术创新者和产品开发供应商。公司开发了700多个专利产品,为表观遗传学方面的研究和新药研发提供全面系统的解决方案。相比普通方法的产品而言,这些独特的产品在科研分析过程中更简单、更快捷、更方便、更有效。全世界的备受推崇的学者、领先的制药企业以及先进的生物技术公司都在使用Epigentek产品。让客户满意和帮助客户在试验中取得最大成功是我们进行技术创新的首要任务。

 

As an epigenetics company, Epigentek Group Inc. is the leading developer and provider of innovative technologies and products for epigenetic-related research. Founded in 2005, the company has since developed a comprehensive portfolio of proprietary products to provide complete and systematic solutions for epigenetics-related research and drug discovery.

 

Epigentek products are used all around the world by esteemed academia, leading pharmaceuticals, and cutting-edge biotechnology companies. These unique products are specifically designed to make assays much simpler, faster, more convenient, and highly more efficient than currently used methods.

 

产品主要有:

(1)Antibodies

DNA Methylation

Histone Modification

RNA Processing & Modification

Chromatin & Transcription

Cellular Structure & Function

Signal Transduction

Metabolism

Immunology & Inflammation

Other Primary Antibodies

Secondary AntibodiesTag Antibodies

Antibody Panel Packs

(2)Research Kits

Sample Preparation

Next Generation Sequencing

DNA Methylation

RNA Methylation

Chromatin & Transcription

Histone Methylation

Histone Acetylation

DNA Damage & Repair

Gene Editing & Silencing

(3)Proteins & Enzymes

DNA Methylation

Modified Histones

Unmodified Histones

Methylated DNA Binding

ADP Ribose

Chromatin Binding/Transcription

DNA Damage & Repair

(4)Peptides

Histone Methylation

Histone Acetylation/Deacetylation

Histone Phosphorylation

(5)Modulators & Inhibitors

DNA Methylation

Histone Acetylation

Histone Deacetylation

Histone Demethylation

Histone Phosphorylation

(7)Reagents

(8)Instruments

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艾美捷科技有限公司

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网站:www.amyjet.com

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Cellular Dynamics.jpg

Cellular Dynamics公司可以大规模从干细胞诱导分化生产人类细胞,用于基础研究,药物发现和再生医学应用。CDI提供了几种末分化的细胞种类作为目录产品:iCell心肌细胞,iCell神经元,iCell内皮细胞和iCell肝细胞。 CDI的MyCell®产品组合能够为客户提供的供体样品进行重编程,基因编辑和分化。该公司还有几种来源于多能干细胞的原型产品,包括iCell心脏祖细胞,iCell造血祖细胞,iCell星形胶质细胞和iCell骨骼成肌细胞等。

 

Fujifilm, once a Company whose core business was photographic film, has diversified and strengthened its portfolio based on developing or acquiring proprietary technologies as well as a deeply held corporate philosophy of enhancing the quality of human lives worldwide. One key area of focus for the Company is Healthcare, and Fujifilm acquired Cellular Dynamics International in May 2015, renamed it to FUJIFILM Cellular Dynamics, Inc.(FCDI) in 2018 to drive innovation in this business area. We see great potential in FCDI as a key component in our mission to be the global leader in regenerative medicine and drug discovery through cutting-edge science and technology.

 

To date FCDI has already achieved leadership in the induced pluripotent stem cell (iPSC) field as one of the only companies in the world to industrially manufacture human cells derived from iPSCs with high quality, purity, and reproducibility and in virtually unlimited quantities. Not only have we achieved this across multiple healthy and diseased donors for the research market but also, we have begun to manufacture human cells under cGMP conditions – a requirement as these human cellular products move from a tool used in drug discovery into a therapy used in regenerative medicine applications.

 

Cellular Dynamics公司的主要产品包括:

iCell Cardiomyocytes

iCell Cardiac Progenitor Cells

iCell Neurons

iCell Astrocytes

iCell DopaNeurons

iCell Hepatocytes 2.0

iCell Hepatoblasts

iCell Skeletal Myoblasts

iCell Endothelial Cells

iCell Hematopoietic Progenitor Cells

iCell Macrophages

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Duchefa Biochemie.png

荷兰Duchefa Biochemie B.V.公司作为DUCHEFA FARMA BV的基础上成立于1989年,而后者50多年来一直为世界各药厂和医院提供生化试剂以及药物原材料。1989年,身处在农业和花草业方面以及国际贸易有着悠久历史的荷兰,Duchefa公司成立了植物组织及细胞培养实验室,开始向世界提供各种高质量植物组培产品。十多年以来,这些产品已经广泛应用在世界各国一流大学的实验室研究,以及植物细胞组织相关的研发中。在Duchefa公司主要提供植物细胞和组织培养基、各种植物生长调节剂、抗生素、植物胶凝、酶作用底物、植物分子生物化学试剂以及种子病原体检测试剂,种类超过400种的试剂用于植物生物技术开发以及植物病理学研究。

Duchefa Biochemie bv offers a whole range of plant tissue culture media, biochemicals, containers, bioreactors and alot of other products needed for micro-propagation. All media are produced in our own laboratories and custom made media are produced for many customers.

 

主要产品类型:

ENZYMES

GELLING AGENTS

GROWTH REGULATORS

PHYTOPATHOLOGICA & MICROBIOLOGY

PLANT TISSUE CULTURE MEDIA

PTC CONTAINERS

REAGENTS & BIOCHEMICALS

UTENSILIA

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艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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艾美捷科技代理AxisPharm品牌全系列产品


AxisPharm是一家专业的分析服务提供商,致力于为科学研究界和工业界提供高质量的分析服务。凭借先进的仪器设备和专业的技术团队,AxisPharm在生物分析、化学分析和质量控制领域树立了良好的声誉。AxisPharm公司的产品线包括:PEG 连接子、用于药物递送的脂质、荧光染料、单击化学试剂、聚聚乙二醇,共聚物、可裂解的连接子、抗体和抗体药物偶联物ADC、ADC 有效载荷、细胞生物学试剂、脱氧核糖核酸、修饰语、探针、合成肽、目标特定链接器、硫醇反应性接头、酸反应性连接子、胺反应性连接子、羰基反应性连接子、探针、修饰符。


AxisPharm页面.png


▍AxisPharm产品线

● PEG连接子:聚合物聚乙二醇是多分散聚乙二醇 (PEG) 聚合物,是一种从石油中提取的聚醚化合物,具有从工业制造到医药的许多应用。

● 用于药物递送的脂质:在药物递送系统中起着至关重要的作用,特别是在脂质体、脂质纳米颗粒或脂质胶束等脂质制剂中。脂质提供结构稳定性,增强药物溶解度,实现控释,并促进靶向药物递送。

● 荧光染料:也称为荧光团或荧光探针,是吸收一种波长的光并以更高波长发射的化合物,从而产生可见荧光。它们是生物学研究中的重要工具,用于标记和检测蛋白质、核酸和细胞等生物分子,从而在显微镜、流式细胞术和实时荧光定量 PCR 等应用中实现灵敏和精确的可视化。

● 点击化学试剂:具有高特异性和最少的副产物,简化了复杂的合成过程。因此,它们在分子生物学、材料科学和药物化学中发挥着至关重要的作用。

● 聚合物聚乙二醇:多分散聚乙二醇 (PEG) 聚合物,是一种从石油中提取的聚醚化合物,具有从工业制造到医药的许多应用。

● 可裂解连接子:一类重要的分子,广泛应用于药物发现、化学生物学和材料科学等各个领域。这些连接子充当两个或多个分子实体之间的连接桥,可以在特定条件下选择性地裂解,从而释放附着的分子。这一特性使它们成为生物活性化合物靶向药物递送、成像和控释的有吸引力的工具。

● 抗体及抗体-药物偶联物及细胞生物学试剂:种类丰富可选择。

● ADC有效载荷:作为 ADC 的三个主要成分之一,有效载荷是高活性和有毒的药物分子,通过化学连接子附着在抗体上。有效载荷可以是小分子、蛋白质毒素、生物活性肽、酶,甚至放射性核素。通过适当的接头与适当的载体系统耦合的有效载荷可能会显示出靶向药物递送的特异性和有效性的提高。

● 脱氧核糖核酸:DNA 是脱氧核糖核酸的缩写,是一种包含所有生物体发育和功能的遗传指令的分子。DNA 由四个基本组成部分组成,称为核苷酸,由糖、磷酸基团和含氮碱基组成。

● 改性剂:改变其他分子或材料特性的化合物。在药物研发领域,改性剂在新型药物递送系统和生物医学设备的设计和优化中发挥着至关重要的作用。一种常见的改性剂类型是官能团,它是赋予分子特定化学和物理性质的原子的特定排列。

● 探针:AxisPharm 提供各种靶标特异性探针,例如叶酸 PEG、生物素 PEG、PROTAC PEG、荧光染料探针和图像探针。探针是一类含有官能团的化合物,旨在选择性地与生物分子(如酶、受体和核酸)相互作用。这些官能团包括荧光染料、生物素和亲和标签等,可以检测和定量复杂生物系统中的特定分子。


Different Types of Polyethylene Glycol PEG Linkers in Stock
Acid PEGDiketone PEGNon-PEG linkerPFP ester PEGSugar PEG β-Glucuronide Linker
Aldehyde PEGDNP PEGPEG-t-butyl esterPhosphonate PEGSulfonic acid PEG
Alkyne PEGDBCO PEGPEG-X-PEGPolymer PEGTCO PEG
Amino PEGDSPE PEGPeptide LinkersPropargyl PEGTetrazine PEG
Aminooxy PEGFluorescent PEGLipid PEGPROTAC LinkerHomobifunctional PEG
Azide PEGFmoc PEGM-PEGSilane PEGBromo PEG
BCN-PEGFolate PEGMaleimide PEGSPDP PEGTosylate PEG
Benzyl-PEGThiol PEGMeNH-PEGBranched PEGBis-Sulfone PEG
Biotin PEGHydrazide PEGNHS ester PEGHyNic PEGDOTA Reagent DOTA PEG
Bis-PEG-acidHydroxy PEGBoc-PEGBis-PEG-NHSIodo PEG
Bis-PEG-NHSCleavable Linkers


Lipids for Drug Delivery
Biotinyl Cap PEDodecanyl PEOther LipidPhosphatidylcholinePhosphatidylethanolamine
Biotinyl PEGlutaryl PEPDP PEPhosphoglycerolPtd Thioethanol
Caproylamine PEIonizable LipidPE MCCPhosphoserineSuccinyl PE
Cationic LipidLipid PEGCyanur PEMPB PE
Fluorescent Dye
AF DyesCyanine DyesMB DyesRhodamine DyeRox (carboxy-X-rhodamine) Dye
APDye FluorsDNP PEGJOER6GPeptide Labeling Reagents
Bodipy ProbesFluorescein (FAM)Pyrene ProbesTAMRA DyeClassic Fluorescent Dyes
IR FluorsQuenchersCoumarin 343

Click Chemistry Tools & Reagents
Alkyne PEGBCN-PEGPTAD LinkerTetrazine PEGClick Chemistry Auxiliary Reagents
Azide PEGDBCO PEGTCO PEGMethylcyclopropene Linkers
Polymer PEG
AcrylateBiotinFmocLipoamideSilane
Active esterBocFolateMaleimideStearic acid
AldehydeCarboxylic acidguanlian1010MW 2000TCO
AmineCholesterolHydrazideMW 5000Thiol
AzideDBCOHydroxylPolysarcosine
Cleavable Linkers
-S-S-CleavablePC CleavableDisulfide LinkersDde Cleavable Linkersβ-Glucuronide Linkers
Cleavable Peptidediazo biotin probesDTSSP crosslinkerPhotocleavable Biotin
Antibody and Antibody Drug Conjugate (ADC)
InotuzumabTrastuzumabEnfortumabLabetuzumab govitecanMirvetuximab soravtansine (solution)
VobramitamabDisitamabMirzotamabLoncastuximab tesirineTrastuzumab deruxtecan (solution)
PolatuzumabOzuriftamabBrentuximabTrastuzumab deruxtecanADC Control Human IgG1-Deruxtecan (DAR 8)
GemtuzumabInebilizumabDatopotamabCofetuzumab pelidotinGlembatumumab vedotin
Daratumumab (PBS)DenintuzumabSacituzumab govitecanBelantamab mafodotinTrastuzumab duocarmazine
PraluzatamabNaratuximabTisotumabEnfortumab vedotin-ejfvTrastuzumab emtansine (solution)
LorvotuzumabRolinsatamabTrastuzumab emtansineTelisotuzumab vedotinEnfortumab vedotin-ejfv (solution)
IzeltabartMipasetamabDatopotamab deruxtecanGemtuzumab ozogamicinBrentuximab vedotin (solution)
LupartumabIladatuzumabORM-5029Cantuzumab ravtansineDepatuxizumab mafodotin
CantuzumabBriobaceptIfinatamab deruxtecanTusamitamab ravtansineADC Control Human IgG1-Deruxtecan (DAR 4)
LonigutamabTamrintamabTisotumab vedotinZilovertamab vedotinDepatuxizumab MMAE
MoxetumomabSacituzumabDisitamab vedotinPolatuzumab vedotinADC Control Human IgG1-vcMMAF
AzintuxizumabUpifitamabBelantamabPivekimabSacituzumab govitecan (solution)
LifastuzumabGlembatumumabPatritumab deruxtecanFarletuzumab ecteribulin
Payloads and Linker modified Payloads
ExatecanBelotecan HClSGD-1882Dolastatin 10MC-Val-Cit-PAB-Doxorubicin
SN 38GimatecanMMAFCalicheamicinGly3-Val-Cit-PAB-MMAE
AmrubicinTaltobulinAuristatin EEribulin MesylateSuO-Glu-Val-Cit-PAB-MMAE
Mitomycin CDxdChlorambucilSoblidotin (Auristatin PE)Fmoc-G-amino-CH2O acetyl-Exetecan
Deruxtecan analogLurtotecanPF-06380101Deruxtecan analog 2DM1-MCC-PEG3-Biotin
sulfo-SPDB-DM4Exatecan mesylateAuristatin FPaclitaxelGGFG-amino-CH2O-acetyl Exetecan
RubitecanMC-DM1MMAF-methyl esterMC-MMD10Mal-PEG8-Val-Cit-PAB-MMAE
(4-NH2)-ExatecanIrinotecanDoxorubicin-SMCCSPDB-DM4DBCO-PEG4-Val-Cit-PAB MMAF
TopotecanPNU-159682MMAD10-HydroxycamptothecinTopotecan Hydrochloride
CL2A-SN38DM47-Ethylcamptothecin

Cell Biology Reagents
Neuro-DiO, lipophilic tracerVU (5-Vinyl-uridine)CM-DiI, lipophilic tracerLumiTracker ER GreenER-Tracker Red (BODIPY TR Glibenclamide)
Annexin V-AF 647 conjugateDAPI, blue fluorescent nucleic acid stainPropidium IodideDeep-Red Fluorescent Nissl StainMitoCLox, mitochondrial lipid peroxidation probe
Annexin V-AF 488 conjugateLumiTracker Mito Rhodamine 123LumiTracker Mito Green FMRAPID DiI, lipophilic tracerLaurdan (6-Dodecanoyl-2-dimethylaminonaphthalene)
Annexin V, His TagThiazole OrangeSynaptoProbe® RedLumiTracker ER RedLinear Polyacrylamide for Nucleic Acid Precipitation
DiD, lipophilic tracerRH 237, potentiometric probeSynaptoProbe® GreenRAPID DiO, lipophilic tracerFluo-4 AM, green fluorescent calcium indicator
DiR, lipophilic tracerHoechst 33342, blue fluorescent nucleic acid stainLumiTracker® Mito Red FMDiI, lipophilic tracerYODi-1, green fluorescent nucleic acid stain
DNA
CPG solid supportsDNA StainsModified Triphosphatesphosphoramidite
Probes
Biotin PEGFolate PEGImage ProbesPROTAC Linker
Amine reactive Linkers
Acid PEGAldehyde PEGBromo PEGMaleimide PEGNHS ester PEG


▍AxisPharm提供的服务

● 蛋白质组学服务:提供质谱分析、蛋白质鉴定和定量服务。专注于生物标志物分析,帮助客户在复杂的生物样本中发现和验证潜在的生物标志物。

● 代谢组学服务:利用先进的LC-MS/MS技术进行代谢物分析,提供通路洞察,帮助客户理解代谢途径和生物过程。

● 高级LC-MS/MS服务:用于PK分析和HPLC分离,确保高精度和高效率的研究结果,提供PK/PD研究,支持药物开发和临床前研究。


▍AxisPharm部分产品列表


Cat#NameM.W.Purity
AP15197Exatecan435.45≥98%
AP15072SN 38392.4≥95%
AP15226Amrubicin483.47≥98%
AP15664Mitomycin C334.3≥98%
AP1520310-Hydroxycamptothecin364.35≥95%
AP152047-Ethylcamptothecin376.41≥95%
AP15210Rubitecan393.35≥95%
AP15211(4-NH2)-Exatecan403.43≥95%
AP15206Topotecan421.5≥95%
AP15207Topotecan Hydrochloride425.5≥95%
AP15202Belotecan HCl433.5≥95%
AP15208Gimatecan447.5≥95%
AP15227Taltobulin473.65≥99%
AP15201Dxd493.48≥95%
AP15209Lurtotecan518.56≥95%
AP15196Exatecan mesylate531.55≥98%
AP15200Deruxtecan analog 2579.58≥95%
AP15205Irinotecan586.68≥95%
AP15224PNU-159682641.62≥98.24%
AP15220Soblidotin (Auristatin PE)701.98≥95%
AP15225SGD-1882725.8≥98%
AP15213MMAF732≥95%
AP15216Auristatin E732≥95%
AP15311Chlorambucil304.21≥98
AP15219PF-06380101743.01≥95%
AP15214Auristatin F746≥95%
AP15215MMAF-methyl ester745.99≥98%
AP15187Doxorubicin-SMCC762.8≥98%
AP15217MMAD771.06≥98%




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Chondrex.png

Chondrex 公司成立于1996年,位于美国的华盛顿州,致力于为全球客户生产高品质的纯化的胶原蛋白、针对胶原蛋白的抗体及ELISA试剂盒产品。凭借Chondrex公司在炎症、胞外基质、结缔组织和免疫学方面的经验,该公司能为风湿性关节炎方面的研究者提供有力工具。

 

Chondrex, Inc. was founded in 1996 to provide high quality research reagents with unparalleled customer support. For over 20 years, Chondrex has been developing and manufacturing products such as highly purified collagen, anti-collagen monoclonal antibodies and a multitude of ELISA kits that provide researchers with the tools necessary to study the pathogenesis of and screen potential therapeutics for rheumatoid arthritis (RA). Through this experience, the scientists at Chondrex have established themselves as experts in inflammation, connective tissue, extracellular matrix, and immunology based research.

 

(1)过敏反应/变态反应

变态反应性IgE 单克隆抗体、小鼠抗-OVAIgE 抗体的配套测定试剂、小鼠总IgE(IgEa 和IgEb)的配套检测试剂、小鼠血清抗-OVA IgE 抗体的配套测定试剂、小鼠抗-OVA IgG 的配套测定试剂

(2)关节炎

制造CAIA(胶原抗体引起的关节炎)模型用的单克隆抗体合剂、用于CIA 和其他研究的胶原(I, II, IX 和XI 型)、免疫接种等级、佐剂、ELISA(酶联免疫吸附试验)等级、T-细胞增殖试验等级、II 型胶原的溴化氰(Cyanogen Bromide-CB)裂解的多肽片段、抗-胶原抗体的配套测定试剂、小鼠抗-I 型和II 型胶原IgG 的配套测定试剂、大鼠抗-I 型和II 型胶原IgG 的配套测定试剂、人/猿猴抗-I 型和II 型胶原IgG 的配套测定试、人/猿猴抗-I 型和II 型胶原IgA 的配套测定试剂、小鼠抗-胶原IgG 亚型的配套测定试剂

(3)研究结缔组织的试剂

人I 型天然胶原的配套检测试剂、II 型天然胶原的配套检测试剂、胶原半定量的配套测定试剂(Sirius Red/Fast Green 染色配套试剂)、胶原免疫染色的配套试剂、II 型胶原染色配套试剂、IX 型胶原染色配套试剂、抗-I 型,II 型和IX 型胶原的单克隆抗体

(4)胶原酶测定

MMP-8 (2型胶原酶)的配套测定试剂、MMP-13 (3型胶原酶)抑制剂的配套测定试剂、荧光标记的胶原(FITC-Labeled Collagen)、重组的人MMP-8和MMP-13

(5)肾炎

诱发大鼠肾炎的单克隆抗体、大鼠尿蛋白的配套测定试剂

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